Saturday, January 31, 2015
Ten Clicks to Reliable Cholesterol Information: Reading through the government’s cholesterol guidelines, Volunteering for a drug test trial, Checking out cholesterol-lowering products, Navigating a cholesterol information quiz and Finding facts about general drugs.
Mouth-Watering Morsels for Special Occasions: Creating healthy munchies with satisfying flavor and crunch and Trying some delicious heart-healthy recipes.
Mouth-Watering Morsels for Special Occasions
In This Chapter
� Creating healthy munchies with satisfying flavor and crunch
� Trying some delicious heart-healthy recipes
When your doc gives you the good news that your cholesterol is under control, you have
cause to celebrate. And even when you’re still working toward lowering your cholesterol, special occasions abound. Unfortunately, party foods, by definition, are full of flavor and not short on fat. But missing your son’s wedding, skipping out on your best friend’s birthday party, or opting not to throw your annual holiday bash isn’t an option.
The good news is that many of the foods recommended for heart health are already standard party fare. Nuts to nibble, avocado in guacamole, smoked salmon with capers, and olives of all sorts are green-light foods. Making sure they’re healthy is just a matter of how you prepare them.
Think of cooking as an art rather than a science. The recipes in this chapter are guidelines; don’t stress if you can’t find the exact ingredients or if your measurements are just a bit off. Adding a little more or less of an ingredient won’t ruin anything, and you just might end up creating something you like even better. The prep time estimates I give you include the time it takes to wash fruits and veggies under cold running water and to cut, assemble, and measure all ingredients. The temperature for all recipes is in Fahrenheit. Also note that the little tomato you see on the “tabs” in front of the recipe names indicate that the recipe is vegetarian.
In this chapter, you discover heart-healthy foods with crunch that haven’t been deep-fried, and satisfying nibbles high in the right sort of fats. I give an assortment of quick and easy recipes for basic party offerings, including a vegetarian pâté and marinated olives. Presentation of food is also part of the drill. Read on to find all sorts of suggestions for creating scrumptious party offerings that meet your dietary needs.
If you love this chapter, check out Low-Cholesterol Cookbook For Dummies by Molly Siple, MS, RD (Wiley) for more great culinary tips and tempting recipes to help get your cholesterol under control.
Little Bites a Cardiologist Would Love
The hors d’oeuvres and little nibbles that meet the nutritional requirements of a cholesterol-lowering, heart-healthy diet are so numerous they would fill a buffet table. These morsels feature raw vegetables, fresh herbs, healthy fats, chicken, and fish. In addition, these foods are eaten in very small amounts, but many are so tasty that you’ll be tempted to make a meal out of them.
Adding crunch to party fare
Healthy foods, perhaps because they’re never deep-fried, often lack crunch, leaving you longing for the sound of crispy food and a satisfying chew. Party favorites like potato chips and tacos are full of crunch, while healthier foods, such as grains, nut butters, and vegetables, are quiet foods. The following gives you ways to combine the best of both worlds: the cholesterol-conscious and the crispy.
Toast is crunchy, so how about starting with that and making some crostini, which means “little toasts” in Italian. Here’s how to prepare crostini:
1. Adjust the rack of a broiler so that it’s at least 4 inches from the heat source and preheat the broiler.
2. Cut a slim baguette of French bread (about 2 inches in diameter and sold in specialty bakeries and upscale supermarkets) into thin slices and place on a large baking sheet.
Cut slices of bread on the diagonal for a stylish presentation.
3. Brush the slices on one or both sides with a little olive oil and rub one or both sides with a halved clove of garlic.
4. Broil the bread so that one side is lightly toasted.
5. Turn the bread over and broil for a minute or two, making sure that the bread doesn’t toast all the way through.
Use crostini as a platform for other foods. Here are some suggested toppings:
� A smear of tapenade, an olive paste seasoned with capers, anchovies, garlic, and lemon juice and sold in jars
� Goat cheese mixed with fresh herbs, such as basil and parsley, and topped with a sliver of sun-dried tomato
� A spoonful of garlicky, mashed cannellini beans scented with oregano
Homemade baked tortilla chips
Instead of noshing on corn chips fried in who-knows-what kind of oil and loads of salt, enjoy the crunch of home-baked tortilla chips. Start with corn tortillas or whole-wheat tortillas, both made with whole grains, far healthier than white flour tortillas. Here’s the procedure:
1. Using a pastry brush, brush each side of a corn tortilla with unrefined safflower oil or lightly spray each side, using an oil sprayer filled with unrefined oil.
To give the chips a southwest flavor, sprinkle the oiled tortillas with ground cumin or chili powder.
2. Stack the tortillas and cut them into 8 wedges, as you would a pie.
3. Place the wedges in a single layer on an ungreased baking sheet and bake in a preheated 400-degree oven, until they just begin to become golden, 10 to 12 minutes.
Serve tortilla chips with a bean dip for a dose of soluble fiber. Or use guacamole, which is a great source of folate, or classic tomato salsa, which is full of healthy ingredients.
Doing the crudité dip
Eating raw vegetables at parties became chic when the veggies took on the name crudité, which is French for “raw.” They are indeed refreshing, crispy, and full of all the vitamins and minerals nature gave them. But what do you do with all the bits of vegetable after you cut them? Choose one of the following ideas to bring order to the chaos:
� Start with sticks of carrot, celery, and seeded cucumber, and maybe some blanched asparagus or blanched string beans, and give each vegetable a separate container, such as glass tumblers, colorful ceramic mugs, or small flower vases. Cluster the containers on the serving table, creating a vegetable forest.
� Arrange vegetables on a long, rectangular platter or basket lined with kale, and give each vegetable its own row.
� Tuck raw vegetables between the leaves of a full head of Boston lettuce, following the instructions in the recipe, Crudité with Mango Salsa and Creamy Avocado Dip.
Figure on 1 cup of dip for every 20 guests. If you’re serving chunky dips, you may need a bit more.
The fat of the matter: Acceptable appetizers
One of the great pleasures of party food is that it’s full of hard-to-resist assertive flavors, in part because the food is also full of fat, a flavor carrier. Taking a holiday from diet restrictions, the most careful of eaters will graciously accept the hot cheese puffs and chocolate truffles being offered. But there’s no reason you can’t enjoy the feel of fat, even if you’re watching your cholesterol. You have options.
Nuts and olives
Nuts and olives are two classic cocktail nibbles that are perfectly acceptable heart-healthy foods. In numerous studies, both nuts and olives, the basis of the famed Mediterranean diet, have been linked to a lower risk of heart dis- ease. In addition, the monounsaturated and polyunsaturated fats in these foods help control cholesterol.
So which nuts have the most of these healthy fats and are low in the cholesterol-raising saturated kind? Here are a few that fit the bill:
� Almonds
� Filberts
� Pecans
� Pistachios
� Walnuts
One way to include nuts in a party menu is to add walnuts to hummus, puree- ing them along with the other ingredients. The rich, mellow flavor of walnuts blends well with the flavors of the other ingredients, and walnuts add omega-3 fatty acids, making hummus even more nutritious. Here’s how to make it: In a food processor, combine 2 cups chickpeas (one 15-ounce can), 1⁄2 cup walnuts, 1⁄2 cup tahini sesame paste, 1⁄4 cup fresh lemon juice, and 1 clove garlic, plus water or oil to reach the desired consistency. Season with cumin and salt.
You can save on fat by eating lowfat and nonfat cheeses or having a soy cheese look-alike, but I can’t promise you great flavor or texture in all cases. For instance, I’d rather have a shaving of world-class Parmigiano-Reggiano as a garnish for slices of pear topped with a paper-thin slice of prosciutto, than a large wedge of rubbery, nonfat mozzarella any day. But do sample some lowfat cheese and see what you think. For instance, lowfat ricotta can be very satisfying. If you want to cut back on fat intake and still eat cheese, modified products let you keep these creamy-tasting foods in your diet.
When shopping for cheese, be sure to read the label for content of total fat and saturated fat as well as cholesterol. The amounts present vary among producers. Cheeses such as Camembert, Brie, Roquefort, cheddar, and American processed cheese can contain more than 25 percent of your daily quota of saturated fat and about 10 percent of a day’s worth of cholesterol. And these amounts are in just 1 ounce, which isn’t very much, especially for a devoted cheese eater. Best to stay away from these unless you can stop after one nibble. Feta and mozzarella, the full-fat kind, are lower in fat and cholesterol and are better choices.
For the feel of fat on the tongue, use lowfat yogurt and lowfat sour cream, both very palatable, in your hors d’oeuvres.
If any food says “special occasion,” it’s caviar. Caviar is salted fish eggs, so, just like chicken eggs, it’s a whole food and a balanced source of nutrition. In addition, although fat contributes 61 percent of the calories, caviar, like fish, contains mostly the healthy monounsaturated and polyunsaturated kinds. Admittedly, caviar is high in sodium (containing 240 mg per tablespoon) and in cholesterol (containing 31.3 mg per teaspoon), but you’re not likely to be eating a bowlful of caviar anyway.
I give you two ways of serving caviar that give you a smidgeon of this glamorous stuff. On a budget, use black lumpfish caviar, golden whitefish caviar, or salmon red caviar, all sold in little jars in supermarkets. Otherwise, invest in some American farm-raised caviar or the even pricier imported sevruga, osetra, or beluga caviar.
1. Boil round, red potatoes, the smallest you can find, until they’re cooked through and tender.
2. Peel the potatoes, slice in half crosswise, and cut some potato off the base of each half, so the potato is steady when placed on a plate.
3. Using a melon baller, cut into the flat surface of each potato half and scoop out a little bowl in the middle.
4. Fill the hollow of each potato with lowfat sour cream and sprinkle the sour cream with caviar.
For this elegant hors d’oeuvre, caviar is displayed on pale chartreuse Belgium endive.
1. Wash a head of Belgium endive and cut it at the base to separate leaves.
2. Using a teaspoon, place a small dollop of lowfat sour cream at the wider end of each leaf and then sprinkle caviar on the sour cream.
3. Garnish the caviar and sour cream with a tiny sprig of dill.
4. On a round serving platter, arrange these like spokes, with the narrow end of the leaf pointing out.
Getting some help: Ready-made appetizers
I often serve canned stuffed grape leaves and no one is the wiser. My guests sometimes even ask for the recipe. You can find heart-healthy, ready-made appetizers in supermarkets or natural foods stores. Offer some of the following on their own or add them to a few of your own appetizers:
� Roasted sweet red peppers
� Marinated artichoke hearts
� Smoked salmon
� Sliced veggies from the salad bar, to serve as crudités with a dip
� Stuffed tortellini (serve it on skewers)
� Freeze-dried vegetable crunchies, such as corn, peas, red bell peppers, carrots, and tomatoes, produced with no added fat and sold in natural food stores
� Canned stuffed grape leaves
Tasty Recipes to Impress Your Guests
The recipes in this section are attractive to the eye, and you and your guests will likely count them among your favorites for regular snacking. The Citrus- Scented Marinated Olives, in particular, are known to be highly addictive!
Some of the following recipes are hearty and healthy enough to be served as a main course as well as party munchies. You can even turn the Mushroom Pâté into a pasta sauce, as I explain in the recipe introduction. Use this section as inspiration — take a look at your favorite heart-healthy meals to see whether you can serve any of them as hors d’oeuvres at your next gathering.
Almonds have more of the monounsaturated fats, the cornerstone of the heart-healthy Mediterranean diet, than any other nut. Scent them with spices, add some raisins, and you’ve created a healthy treat. The small amount of butter in this recipe imparts its inimitable flavor without adding much saturated fat. When nuts are toasted in this way, they don’t absorb much of the cooking oils because they already contain a large amount of fat. Serve this snack with cocktails or after-dinner coffee.
1 In a skillet over medium heat, melt the butter and combine with the oil.
2 Add the almonds and toss to coat with the oil. Sprinkle the almonds with the cinnamon, ginger, and nutmeg and toss to combine ingredients. Toast, stirring occasionally, for 5 minutes.
3 Add the raisins and continue to cook the almond mixture until the nuts begin to brown, an additional 2 to 3 minutes. Season to taste with salt. Make sure to cool the nuts completely before storing.
Put one of these olives in your mouth, close your eyes, and you can taste summer in Provence! Let the Mediterranean flavors transport you. This recipe uses brine-cured olives, but if you want to cut back on salt, ordinary canned olives work fine as well. Use pitted ones so that more of the marinade can find its way into the olives. You can also marinate these olives in olive oil, but I use water here to cut back on calories and create a lighter taste.
1 tablespoon grated orange peel 1 tablespoon grated lemon peel 2 bay leaves
2 anchovies, minced, or 2 tablespoons anchovy paste
1⁄2 teaspoon dried thyme
1 Combine the olives, garlic, orange juice, lemon juice, orange peel, lemon peel, bay leaves, anchovies, and thyme in a glass jar with a tight-fitting lid.
2 Add enough water to the citrus marinade to cover the olives.
3 Seal the jar with the lid and shake the jar several times to distribute and combine the ingredients.
4 Refrigerate the olives for 3 days, shaking the jar once each day to keep the marinade well mixed.
Go-With: Serve the olives with goat cheese and a baguette of French bread.
Skewered Scallop Seviche with Avocado
Seviche, popular in Latin America, is raw fish that has been marinated in citrus juice, usually lime. The acid in the fruit “cooks” the fish. Any white-fleshed fish or scallops can be prepared this way. Shellfish has a reputation for being high in cholesterol, but a serving of 4 skewers of these scallops contains only 16 mg of cholesterol.
1 In a shallow 8-inch square baking dish, combine the juice, cilantro, onion, and garlic.
2 Rinse the scallops. If necessary, remove the tough, stark white hinge that attaches the scallop to the shell. Place the scallops in the lime juice marinade. Cover and refrigerate a minimum of 4 hours, or overnight. The scallops are “cooked” when they’re opaque.
3 Cut each tomato in half crosswise. Peel and remove the seed of the avocados and cut them into 3⁄4-inch cubes. The cubes need to be substantial enough so that they don’t fall off the skewer. Drain the seviche and season to taste with salt and pepper.
4 Assemble the skewers by threading the components in this order: 1 scallop, 1 cube avocado, 1 scallop, and 1 cherry tomato half. Run the skewer through the center of the face of the tomato where it was cut and then out the top through the skin, so the tomato becomes a cap on the other foods.
5 On a round platter, arrange the skewers of seviche like spokes of a wheel, with the tomato caps at the center. Or use a horizontal tray and place the skewers in a row with the food colors forming stripes.
Crudités with Mango Salsa and Creamy Avocado Dip
The inspiration for this recipe is a delicious combo dip I buy ready-made, a container with a layer of fresh guacamole topped with a layer of mango salsa. The combination of smooth and spicy is just right. The Creamy Avocado Dip included here is full of healthy monounsaturated fats and is high in folic acid, while the Mango Salsa gives you an effortless way to increase your fruit intake. For the crudités, try using only green and white vegetables, like I suggest here, for a designy, high-style look.
1 Taking the base of a head of Boston lettuce in one hand, gently open the leaves of the lettuce with the other hand, wiggling your fingers down between the leaves. (If the lettuce is sandy, submerge the opened head in a sink filled with water and briefly swish to loosen dirt. Drain upside down in an empty dish rack before proceeding.)
2 Meanwhile, peel the turnip and cut in 1⁄4-inch rounds. Picture the turnip slice as the earth and cut a small V-shaped wedge at the North Pole and South Pole. Also make two V-shaped wedges at each end of the “equator.”
3 Bring about an inch of water to boil in a skillet and add the asparagus. Cook until the asparagus is bright green and al dente, about 2 minutes. Remove with tongs, and sub- merge the asparagus spears in a bowl of cold water until they reach room temperature.
4 Tuck the turnip slices, asparagus, endive leaves, and cucumber between the lettuce leaves. Serve with the Mango Salsa and Creamy Avocado Dip.
Vary It! If you decide your crudité composition is begging for more color, add carrot sticks.
Tip: If the Boston lettuce on display has had the outside leaves removed, ask the produce manager where you shop to bring you a full and untrimmed head from the cartons of pro- duce stored in the back.
Per serving: Calories 8 (From Fat 1); Fat 0g (Saturated 0g); Cholesterol 0mg; Sodium 8mg; Carbohydrate 2g (Dietary Fiber 1g); Protein 1g.
Mango Salsa
This recipes lives and dies on whether the mango is sweet with a smooth texture, so chose your mango with care. When ripe, a mango yields to gentle pressure like a ripe avocado, and the stem end has a gentle aroma. Choose plump mangos, avoiding those with bruised or shriveled skin. This nonfat mix of healing fruits and vegetables also goes great with chicken and fish.
1 Put the mango, sweet red pepper, onion, chile, cilantro, and lime juice in a mixing bowl. Toss gently to combine the ingredients.
2 Season to taste with salt and serve immediately.
Per serving: Calories 16 (From Fat 9); Fat 1g (Saturated 0g); Cholesterol 0mg; Sodium 20mg; Carbohydrate 2g (Dietary Fiber 1g); Protein 0g.
Creamy Avocado Dip
Sour cream dips have just the right tartness to complement the sweetness of fresh, raw vegetables. Cut the saturated fat of the cream by making the dip with lowfat or nonfat sour cream, and as in this recipe, substituting some of the sour cream with avocado to add healthier fats.
1 Put the sour cream in a food processor fitted with a metal blade.
2 Add the cumin to the sour cream in the processor, and then add the avocado, garlic, and cilantro. Process until smooth, scraping down the side of the processor bowl if necessary to incorporate all the ingredients.
3 Season to taste with salt and pepper. Transfer the dip to a small serving bowl and garnish with chopped cilantro. Serve immediately. (The dip can also be prepared earlier the same day you plan to serve it. Press plastic wrap onto the surface of the dip so that no air comes in contact with the avocado in the dip to keep it from turning brown. Refrigerate until ready to serve and add the cilantro garnish right before serving.)
With its hearty texture, rich brown hues, and a dash of sherry, this vegetarian mush- room pâté is much more than a passable substitute for the regular pork and liver versions. Instead, cashews are added as a source of oils. This pâté is such a winner that I experimented thinning it with a little white wine and making it into a pestolike pasta sauce, served with penne. It worked!
1 In a large, heavy skillet over medium heat, heat 4 tablespoons of the oil and add the shallots, garlic, and mushrooms. Cook until the mixture begins to brown and all the liquid evaporates, stirring frequently, 15 to 20 minutes, depending on the moisture content of the mushrooms. Remove the skillet from the heat.
2 In a food processor fitted with a metal blade, chop the cashews until they have a fine texture. Add the remaining 1 tablespoon oil and continue to process to make a coarse paste.
3 Add the mushroom mixture, basil, parsley, and sherry. Pulse the processor on and off until the pâté has a coarse texture. Season to taste with the salt and pepper.
4 Transfer the mushroom pâté to a small ceramic loaf pan, or a bowl lined with plastic wrap so you can easily pop out the pâté. Cover and chill 4 hours. Serve in the loaf pan, or turn the pâté out of the bowl and garnish with sprigs of parsley. Enjoy on crostini.
Identifying Meds That Raise Cholesterol: Finding the facts on hormones and HDLs, Discovering how diuretics affect blood fats, Protecting statins and Naming the problems with vasoconstrictors.
Identifying Meds That Raise Cholesterol
In This Chapter
� Finding the facts on hormones and HDLs
� Discovering how diuretics affect blood fats
� Protecting statins
� Naming the problems with vasoconstrictors
Believe it or not, several common medications, such as diuretics (also known as water pills), work like a dream to cure or alleviate conditions they were designed to treat, such as swelling caused by water retention, but may send your “bad” cholesterol up, your “good” cholesterol down, and your triglycerides heaven- knows-where (see the section “Lowering Fluids with Diuretics” later in this chapter).
The following sections make up a representative list of medicines that may alter your cholesterol levels, sending some kinds of cholesterol up and others down. But hey, forewarned is forearmed.
Hankering for Hormones
In the past few decades, hormone products have become part of everyday life. The female sex hormones estrogen and progesterone are used for birth control, “morning after” pills, and postmenopausal hormone replacement therapy. Some athletes skirt the law by using steroids (male hormones) to build muscles. In each case, the use of hormones, like the ones listed in this section, can have unexpected effects on cholesterol levels.
Birth control pills
The most popular oral contraceptives (OCs) are a combination of the female hormones estrogen and progestin (a synthetic form of progesterone, the second female sex hormone). The less effective and thus less frequently used “mini- pill” is plain progestin.
Estrogen seems to be the more cholesterol-friendly female hormone. Estrogen lowers total cholesterol and boosts HDLs, the “good” cholesterol. But higher doses of progestins lower HDLs. You can read all about it for yourself in this quote from the package insert that comes with all OCs sold in the United States:
A positive association has been observed between the amount of estrogen and progestogen [another way to say “progestin”] in oral contraceptives and the risk of vascular disease. A decline in serum high-density lipoproteins had been reported with many progestational agents. Estrogens increase HDL cholesterol. The net effect of oral contraceptives depends on a balance achieved between doses of estrogen and progestogen. Most scientists now believe that the reason women on hormone replacement therapy had a higher incidence of heart attacks is because the therapy stimulates the clot- ting system, and since the first event in a heart attack is a clot forming in the coronary arteries, that is the reason for the increased number of heart attacks and not the effects of cholesterol.
Hormone replacement therapy (HRT)
Now that researchers have proven the link between HRT and a higher risk of breast cancer and disproved the assumption that taking hormones after menopause lowers a woman’s risk of heart disease, fewer women are using these pills.
For those who do — or for those women who take estrogen for a few weeks or months after a surgical menopause (translation: total hysterectomy that removes both the uterus and the ovaries) — I want to point out that estrogen does increase levels of HDLs. Wait. I already said that in the preceding section.
Table 13-1 lists the words used for “estrogen” or “progestin” on the labels for birth control pills and postmenopausal hormone-therapy products.
Muscle builders
The male sex hormone testosterone promotes muscle mass, which is why the average man has bigger biceps than the average woman.
In medicine, anabolic androgenic steroids (muscle-building, testosterone-like compounds) are used legally to treat the results of abnormally low levels of testosterone, such as delayed male puberty, some forms of impotence, and the wasting of lean muscle mass associated with certain illnesses — AIDS being one of them.
Although these meds are banned from all legitimate athletic competition, some athletes use them secretly in an attempt to enhance performance. In the long run, it’s a losing game. According to the National Institute on Drug Abuse (www.nida.nih.gov), steroid abuse — using the drugs to build muscles for athletic competition — comes with a full complement of horrible side effects, including liver tumors; liver cancer; yellowish pigmentation of skin, tissues, and body fluids; high blood pressure; kidney tumors; severe acne; trembling; shrunken testicles; infertility; increased risk of prostate cancer; male pattern baldness (in men and women) . . . no, no, I can’t go on. This book is called Controlling Cholesterol For Dummies, not Steroids For Dummies, so I have to stick with the main event: Taking anabolic androgenic steroids raises LDLs and lowers HDLs. No gold medal there, guys.
Lowering Fluids with Diuretics
Diuretics are drugs that make you urinate more frequently, eliminating excess fluids from your body tissues. Some ingredients, such as caffeine, in over-the- counter (OTC) products have a diuretic effect, but the most effective diuretics are the ones available only by prescription.
Common prescription diuretics
Prescription diuretics may be either single ingredient products or combination products. The active ingredient in a single ingredient prescription diuretic is most commonly either furosemide, spironolactone, or a member of the thiazide drug family. Table 13-2 lists some well-known single ingredient prescription diuretics.
The primary active ingredient in combination diuretic products is commonly a thiazide diuretic. The second active ingredient varies according to what the drug is designed to accomplish. This is done because diuretics make most blood-pressure-lowering drugs work better. For example:
� The active ingredients in Aldochlor are a thiazide diuretic (chlorothiazide) and methyldopa, a drug that lowers blood pressure by relaxing blood vessels.
� The active ingredients in Aldactazide are a thiazide diuretic (hydrochlorothiazide) and spironolactone, a drug that reduces the amount of the mineral potassium lost when you take a diuretic and urinate a lot (yes, your body eliminates potassium through urinating).
� The active ingredients in Lopressor HCT are a thiazide diuretic (hyrochlorothiazide) and metroprolol tartrate, a drug that helps control the rapidity and force of your heartbeat.
Diuretics and cholesterol levels
Taking either a thiazide or furosemide diuretic raises total cholesterol levels and levels of triglyerides (another blood fat described in Chapter 2). The increase, however, is believed to be small enough that it doesn’t increase the risk of heart disease. Because diuretics are so valuable for controlling high blood pressure, your doctor can work with you to establish a diet that helps control your cholesterol while allowing you to continue taking the water pills.
Any medicine, prescription or over-the-counter, that causes you to lose too much water can have serious effects, like causing you to collapse from dehydration. That’s why you should never use diuretics without the knowledge or consent of your own personal physician.
Sabotaging Cholesterol Therapy
Your cholesterol is on the high side, so your doctor prescribes a cholesterol- lowering statin drug, such as atorvastatin (Lipitor), pravastatin (Pravachol), or simvastatin (Zocor), or a statin combo drug, such as Vytorin. You take the pills right on schedule, but when your doctor tests your blood, your cholesterol level hasn’t gone down. Why? One possibility is that you’re taking a second medication that makes your statin less effective. Gee. Sometimes you can’t win for losing.
Considering interactions between cholesterol and meds, I thought it important to mention statin interactions. But for more on how the other meds you take can affect a statin’s ability to control your cholesterol, turn back to Chapter 12, which has absolutely everything you need to know about statins and other cholesterol-lowering drugs, including these pesky drug/drug interactions.
Narrowing Your Options
Having high cholesterol is risky because cholesterol particles in your blood- stream may snag on artery walls, catch other particles floating by, and build plaque deposits that block the artery, stop the normal flow of blood to your heart, and trigger a heart attack. Given this set of facts, you can understand why medicines that further narrow the blood vessels may be problematic for someone with high cholesterol or known coronary artery disease.
Drugs that make blood vessels constrict (narrow down) are called vasoconstrictors. Drugs that make blood vessels dilate (open wider) are called vasodilators. Vasoconstrictors raise your blood pressure and vasodilators lower it.
Vasoconstrictors are used in both prescription and OTC medicines, as you can see here:
� An example of a prescription vasoconstrictor product is the Epipen, a device that enables the patient to inject a dose of epinephrine.
� An example of an OTC vasoconstrictor product is a cold remedy, cough medicine, or anti-asthma product in which the vasoconstrictor functions as a decongestant, an ingredient that helps shrink swollen tissues in your nose and throat. Hemorrhoid relief products may also contain vasoconstrictors, but you apply them to your skin, so they’re less likely to be problematic.
By the way, if you’re still smoking, you should know that nicotine is a vasoconstrictor. For more about smoking and your cholesterol, check out Chapter 9.
Right now, take a look at Table 13-3, which contains a list of common decongestant ingredients from the Physicians’ Desk Reference 2001. All these ingredients are vasoconstrictors, so if you have high cholesterol, you want to ask your doctor before using these products.
Getting the Last Word
Every drug can be valuable — heck, even lifesaving — when prescribed for the condition it’s intended to treat and for a patient whose body tolerates the medicine. On the other hand, every drug has side effects. And sometimes a drug that works for one person is ineffective or downright dangerous for another person.
The trick is to maximize the benefits and minimize the risks. In other words, try to knock off the illness or medical condition without harming the patient. Doing that requires you and your doctor to work together. She by doing her homework so she knows what may go wrong; you by taking your meds as directed and reporting any problems immediately. And each of you needs to listen to one another. It’s a hard job, but you can do it. So do it.










