triglycerides range (level)

What is Triglycerides (TGs) level (range) test is for?

Triglycerides (TGs) identify the risk of developing coronary heart disease (CHD). This test is part of a lipid profile that includes the measurement of cholesterol and lipoproteins. This test is also performed on patients with suspected fat metabolism disorders.

What is Triglycerides (TGs) test explanation?

Triglycerides (TGs) are a form of fat in the blood stream. They are transported by very-low density lipoproteins (VLDLs) and low density lipoproteins (LDLs). Triglycerides (TGs) are produced in the liver using glycerol and other fatty acids as building blocks. Triglycerides (TGs) act as a storage source for energy. When Triglycerides (TGs) levels in the blood are high, Triglycerides (TGs) are deposited in the fatty tissues. Triglycerides (TGs) constitute most of the fat in the body and are a part of a lipid profile that also evaluates cholesterol and lipoprotein. A lipid profile is performed to assess the risk of coronary and vascular disease

What are the Triglycerides (TGs) test interfering factors?

• · Ingestion of fatty meals may cause elevated Triglycerides (TGs) levels.
• · Ingestion of alcohol may cause elevated levels of Triglycerides (TGs) by increasing the production of VLDL.
• · Pregnancy may cause increased levels.

What are the drugs that may affect Triglycerides (TGs) test result?

• · Drugs that may cause increased TG levels include cholestyramine, estrogens, and oral contraceptives.
• · Drugs that may cause decreased levels include ascorbic acid, asparaginase, clofibrate, colestipol, fibrates, and statins.

What is Triglycerides (TGs) test result clinical significance ?

• · triglycerides level high

1. o Glycogen storage disease (von Gierke disease): VLDL (TG-carrying proteins) synthesis is increased, whereas catabolism is decreased. TG levels in the blood increase.
2. o Familial hypertriglyceridemia: This is a genetic predisposition to elevated TGs.
3. o Apoprotein C-II deficiency: This congenital disease is associated with lipoprotein lipase deficiency. TGs accumulate.
4. o Hyperlipidemias: As lipids in the blood increase, so does TG, the major blood lipid.
5. o Hypothyroidism: Catabolism of TG is diminished.
6. o High-carbohydrate diet: Excess carbohydrates are converted into TG and blood levels of TG rise.
7. o Poorly controlled diabetes: Diabetics have an increased synthesis of TG carrying VLDL and a decreased catabolism of the same. Therefore TG blood levels increase.
8. o Nephrotic syndrome: The loss of proteins diminishes the plasma oncotic pressures. This appears to stimulate hepatic lipoprotein synthesis of VLDL and LDL. Also, lipoprotein disposal is possibly diminished.
9. o Chronic renal failure: Insulin levels are high in these patients, because insulin is excreted by the kidney. Insulin increases lipogenesis and causes TG levels to increase. Also, these patients have a deficiency in lipoprotein lipase that clears the blood of TG.

• · triglycerides level low

1. o Malabsorption syndrome: These patients have a malabsorption of fat from the diet. As TG is the major component of dietary fat, TG levels can be expected to fall in light of poor gastrointestinal (GI) absorption.
2. o Abetalipoproteinemia: Not only do these patients have a malabsorption of fat, but they also have a defective synthesis of apoprotein B (TG-carrying lipoproteins). TG blood levels are low.
3. o Malnutrition: These patients have diminished fat in the diet. As TG is the major component of dietary fat, TG levels can be expected to fall.
4. o Hyperthyroidism: The catabolism of VLDL, the main TG-carrying lipoprotein, is increased. Therefore, TG blood levels diminish.

What is the normal result of Triglycerides (TGs) test ?

Adult/elderly

• · Male: 40-160 mg/dL or 0.45-1.81 mmol/L (SI units)   
• · Female: 35-135 mg/dL or 0.40-1.52 mmol/L (SI units)

mg/dL: A gram per liter or liter is a unit of measurement of mass concentration that shows how many grams of a certain substance are present in one liter of a usually liquid or gaseous mixture

mmol/L: Millimoles per liter, a unit of measure that shows the concentration of a substance in a specific amount of fluid. In most of the world, except for the United States, blood glucose test results are reported as mmol/L. In the United States, milligrams per deciliter (mg/dL) is used

Children(yr)	Male(mg/dL)	Female(mg/dL)
0-5	30-86	32-99
6-11	31-108	35-114
12-15	36-138	41-138
16-19	40-163	40-128

What are the Triglycerides (TGs) test Critical Values?

The Critical Values of triglycerides level is >400 mg/dL